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Monitoring the Critically Ill Patient is an invaluable, accessible guide to caring for critically ill patients on the general ward. Now fully updated and improved throughout, this well-established and handy reference guide text assumes no prior knowledge and equips students and newly-qualified staff with the clinical skills and knowledge they need to confidently monitor patients at risk, identify key priorities, and provide prompt and effective care. This new edition includes the following five new chapters: Monitoring the critically ill child Monitoring the critically ill pregnant patient Monitoring the patient with infection and related systemic inflammatory response Monitoring a patient receiving a blood transfusion Monitoring pain

The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.

Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids presents a thorough overview of nucleic acid chemistry—a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids—such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs—to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy. Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes: In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry A close look at a large range of current topics on nucleic acid chemistry and biology Essential information on the use of nucleic acid drugs to treat diseases like cancer A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research area Thorough in its approach and promising in its message, Medicinal Chemistry of Nucleic Acids probes the new domains of pharmaceutical research—and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.

Providing a broad overview of the microbial pathogens associated with hospital-acquired human illness, Techniques for the Study of Hospital Acquired Infection examines the cost-effective use of laboratory techniques in nosocomial infectious disease epidemiology and control. This concise guide addresses the cost benefits of combining modern molecular techniques with the traditional activities of infection control departments. The book is useful as a guide to hospital infection control programs as well as a text for medical practitioners, grad/medical students, researcher scientists, population biologists, molecular biologists, and microbiologists.

“This textbook, Radiation Oncology in Palliative Cancer Care, represents the full evolution of radiation therapy, and of oncology in general. ( … ) [It] is an acknowledgment that palliative radiotherapy is now a sub-specialty of radiation oncology. This formally makes palliative radiotherapy a priority within patient care, academic research, quality assurance, and medical education.” – From the Foreword by Nora Janjan, MD, MPSA, MBA, National Center for Policy Analysis, Dallas, TX, USA Palliative Medicine is the professional medical practice of prevention and relief of suffering and the support of the best possible quality of life for patients and their families, regardless of the stage of the disease or the need for other therapies. The most common cause for palliative care referral is terminal cancer, and a large proportion of those referrals include patients who will need palliative radiotherapy during the course of their disease. Still, there are barriers to coordinated care between radiation oncologists and palliative care physicians that differ from one country to another. Until now, one overarching limitation to appropriate concurrent care between the specialties across all countries has been the lack of a comprehensive yet concise reference resource that educates each of the specialties about the potential synergistic effects of their cooperation. This book fills that void. Radiation Oncology in Palliative Cancer Care: Is the first book-length treatment of this important topic available on the market Is authored by world-renowned experts in radiation oncology and palliative medicine Uses a multidisciplinary approach to content and patient treatment Features decision trees for palliative radiotherapy based upon factors such as patient performance status and prognosis Pays careful attention to current best practices and controversies in the delivery of end-of-life cancer care This book is an important resource for practicing radiation oncologists and radiation oncologists in training, as well as hospice and palliative medicine physicians and nurses, medical oncologists, and geriatricians.

Veterinary Techniques for Llamas and Alpacas provides a step-by-step guide to performing procedures in llamas and alpacas. Organized by body system, the book presents concise, visually oriented information to enable clinicians to treat these animals with confidence. With coverage ranging from basic maintenance such as restraint and catheterization to more complex procedures such as minimally invasive surgery, Veterinary Techniques for Llamas and Alpacas describes the full range of techniques required for the medical management of these species. Each procedure is described in detail, with a consistent format for ease of use and accompanying photographs to illustrate the concepts described. A companion website offers videos of many of the procedures discussed in the book. Veterinary Techniques for Llamas and Alpacas is an essential resource for any veterinarian or technical staff member treating South American camelid patients.

The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately. Flow cytometry is key in this diagnostic pathway. This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At the core of this text is an appreciation of clinical, morphological and immunophenotypic correlation and the importance of constant liaison and discussion between the medical and scientific teams. The authors present a logical and practical approach to the diagnosis of blood disorders (both neoplastic and reactive) and evaluate the diagnostic applications of flow cytometry. Practical Flow Cytometry in Haematology Diagnosis provides: • A clinical reference source on all aspects of flow cytometry, covering both malignant and benign conditions • Carefully chosen real-life cases in each chapter, complemented by high quality morphological images • Help in making a diagnosis, together with an understanding of the limitations of the technique and the potential pitfalls All those who instigate, perform, interpret or act upon flow cytometry patient material will find this book an invaluable guide.

Morson and Dawson’s Gastrointestinal Pathology 5th Edition Edited by Neil A. Shepherd, DM, FRCPath, Gloucestershire Cellular Pathology Laboratory, Cheltenham, UK; Bryan F. Warren, MB, ChB, FRCP (London), FRCPath, John Radcliffe Hospital, Oxford, UK; Geraint T. Williams, OBE, BSc, MD, MRCR, FRCP (London), FRCPath, FMedSci, Cardiff University, Cardiff, UK; Joel K. Greenson, MD, University of Michigan Medical School, Ann Arbor, MI, USA; Gregory Y. Lauwers, MD, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Marco R. Novelli, MB, ChB, PhD, FRCPath, University College Hospital, London, UK Emphasizing the important role the gastrointestinal pathologist now plays in patient management, Morson and Dawson’s Gastrointestinal Pathology, 5th Edition, is a comprehensive resource for both training and practice. This revision of a “gold standard” textbook reflects current practice, where the abundance of surgical specimens and the revolution in endoscopy has made virtually the entire gastrointestinal tract accessible to biopsy. Generations of practitioners valued Morson and Dawson’s candid guidance, highly readable text, and abundant, high-quality illustrations. This edition preserves those popular features and, to add an international dimension, now includes authors from North America, the European continent, Asia, and Australia. Authors write on their areas of expertise, with chapters organized into seven major parts: Oesophagus Stomach Small Intestine Appendix Large Intestine The Anal Region Peritoneum Each part opens with a chapter on normal anatomy, dissection, and relevant histology. The following chapters describe the morphology, pathogenesis, and aetiology of specific disorders and incorporate developments in molecular pathology and immunohistochemistry. A concluding chapter in each part summarizes miscellaneous conditions of that organ. More than 700 colour images throughout the text illustrate the discussion. An associated website contains all the figures for easy downloading into presentations. With outstanding contributions from the world’s leading gastrointestinal pathologists and a wealth of new information, Morson and Dawson’s Gastrointestinal Pathology, 5th Edition, will serve a new generation of gastrointestinal pathologists, gastroenterologists, and pathologists as the definitive reference for the field.

A Critical Resource with Information You Won't Find Anywhere Else. Dentists of all specialties prescribe drugs for their patients, from pain medications to sedatives to antibiotics, and know all too well that making an evidenced-based decision on which drug to prescribe is more than just looking up a drug on the computer or PDA and requires more comprehensive consideration than the current drug reference books offer. For example, should an antibiotic be prescribed for implant placement or for sinus augmentation procedures? If so, what antibiotic is recommended (backed up with references), when should it be started, and for how long? Which is the antibiotic of choice for an odontogenic infection and how do you know if that antibiotic is working? Improve Your Decision Making with this Essential Guide. The Dentist’s Drug and Prescription Guide is the only book to offer comprehensive coverage of this topic and has quickly become the go-to reference for dental students, general dentists, periodontists, oral surgeons, dental hygienists. Written for dental professionals seeking quick advice on prescribing medications for their patients, the book offers: An easy-to-read question-and-answer format, the text describes evidenced-based pharmacologic therapy with current and up-to-date references regarding adjunctive pharmacologic treatment of the dental patient Easy-to-follow drug tables that summarize the main pharmacologic features of the different disciplines, including periodontics, implantology, oral surgery, and endodontics, with recommendations for pharmacologic treatment with periodontal and implant surgery as well as treatment of periodontal diseases, dental pain, and infection Detailed strategies to manage and prevent drug interactions in the dental practice Instructions and guidelines for the patient on how to take the drugs (e.g., to avoid GI upset when taking antibiotics acidophilus or yogurt can be taken). Plus, sample prescriptions, coverage of proper documentation in the patient's chart, and more! Order your copy today!

Medical Microbiology and Infection Lecture Notes is ideal for medical students, junior doctors, pharmacy students, junior pharmacists, nurses, and those training in the allied health professions. It presents a thorough introduction and overview of this core subject area, and has been fully revised and updated to include: Chapters written by leading experts reflecting current research and teaching practice New chapters covering Diagnosis of Infections and Epidemiology and Prevention & Management of Infections Integrated full-colour illustrations and clinical images A self-assessment section to test understanding Whether you need to develop your knowledge for clinical practice, or refresh that knowledge in the run up to examinations, Medical Microbiology and Infection Lecture Notes will help foster a systematic approach to the clinical situation for all medical students and hospital doctors.

Whereas other textbooks mix a clinical approach with large amounts of the basic science of gastroenterology, this book concentrates on providing practicing gastroenterologists with 100% clinically focused, evidence-based chapters on how to correctly diagnosis and treat all disorders of the digestive tract. Once again, the book is divided into 4 clear parts: Symptoms, Syndromes and Scenarios; Diseases of the Gut and Liver; Primer of Diagnostic Methods; and Primer of Treatments. An accompanying website contains more than 85 high-definition surgical videos of diagnostic and therapeutic endoscopic procedures, 300 MCQs written to mirror the American College of Gastroenterology postgraduate course exams, more than 35 management protocol charts for different diseases, and 850+ illustrations for use in scientific presentations.

Pharmaceutical microbiology has a bearing on all aspects of pharmacy, from the manufacture and quality control of pharmaceutical products through to an understanding of the mode of action of antibiotics. Fully revised and restructured, drawing on the contributions of subject experts, and including material relevant to the European curricula in pharmacy, the eighth edition covers: biology of micro-organisms pathogens and host response prescribing therapeutics contamination and infection control pharmaceutical production current trends and new directions Hugo and Russell’s Pharmaceutical Microbiology, a standard text for Schools of Pharmacy for seven editions, continues to be a user-friendly and authoritative guide for both students and practitioners of pharmacy and pharmaceutical microbiology. 'Highly Commended' in the Pharmacology section of the 2012 BMA Book Awards