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Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

The Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health. Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain. This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: • Influenza Perspectives • Structure and Replication • Evolution and Ecology • Epidemiology and Surveillance • Immunology • Vaccines and Vaccine Development • Clinical Aspects and Antivirals • Public Health Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.

This fully updated edition of Infectious Disease Surveillance is for frontline public health practitioners, epidemiologists, and clinical microbiologists who are engaged in communicable disease control. It is also a foundational text for trainees in public health, applied epidemiology, postgraduate medicine and nursing programs. The second edition portrays both the conceptual framework and practical aspects of infectious disease surveillance. It is a comprehensive resource designed to improve the tracking of infectious diseases and to serve as a starting point in the development of new surveillance systems. Infectious Disease Surveillance includes over 45 chapters from over 100 contributors, and topics organized into six sections based on major themes. Section One highlights the critical role surveillance plays in public health and it provides an overview of the current International Health Regulations (2005) in addition to successes and challenges in infectious disease eradication. Section Two describes surveillance systems based on logical program areas such as foodborne illnesses, vector-borne diseases, sexually transmitted diseases, viral hepatitis healthcare and transplantation associated infections. Attention is devoted to programs for monitoring unexplained deaths, agents of bioterrorism, mass gatherings, and disease associated with international travel. Sections Three and Four explore the uses of the Internet and wireless technologies to advance infectious disease surveillance in various settings with emphasis on best practices based on deployed systems. They also address molecular laboratory methods, and statistical and geospatial analysis, and evaluation of systems for early epidemic detection. Sections Five and Six discuss legal and ethical considerations, communication strategies and applied epidemiology-training programs. The rest of the chapters offer public-private partnerships, as well lessons from the 2009-2010 H1N1 influenza pandemic and future directions for infectious disease surveillance.

Practical Transfusion Medicine, Fourth Edition Edited by Michael F. Murphy, Professor of Blood Transfusion Medicine, University of Oxford; Consultant Haematologist, NHS Blood and Transplant and Oxford University Hospitals, Oxford, UK Derwood H. Pamphilon, formerly Consultant Haematologist, NHS Blood and Transplant; Honorary Clinical Reader, Department of Cellular and Molecular Medicine, University of Bristol, Bristol, UK Nancy M. Heddle, Director, MTRP, Professor, Department of Medicine, McMaster University, Hamilton, Ontario, Canada The pace of change in transfusion medicine is relentless, with new scientific and technological developments. In addition, efforts are continuing to improve clinical transfusion practice and avoid the use of blood wherever possible. This fourth edition continues to be a concise and comprehensive guide to transfusion medicine. It has been thoroughly revised and updated throughout. The scope of the book has been broadened by including more international authors and a new co-editor, Professor Nancy Heddle, an expert in evidence-based transfusion medicine. Practical Transfusion Medicine is divided into seven main parts, each of which guide the reader systematically through the key areas of the speciality: – Principles of transfusion medicine – Complications of transfusion – Practice in blood centres and hospitals – Clinical transfusion practice – Alternatives to transfusion – Cellular and tissue therapy and organ transplantation – Development of the evidence base for transfusion This book is ideal for trainee/resident haematologists revising for examinations and as a reference source for clinical and scientific staff working in the field of transfusion medicine. Titles of related interest Klein: Mollison’s Blood Transfusion in Clinical Medicine, 11e ISBN 9780632064540 (forthcoming 2013) De Vries: Hemovigilance: An Effective Tool for Improving Transfusion Safety ISBN 9780470655276 (August 2012) McCullough: Transfusion Medicine, 3e ISBN 978144433705 (December 2011)

Illustrating the differences between urgent interventions and interventions performed to manage chronic conditions the authors present the chapters in a consistent template for ease of use covering; background, indications, evidence review, device description, procedural techniques, follow-up care, and complications. Shows the differences between interventions performed to manage chronic conditions and interventions that are truly urgent Chapters follow a consistent structure from background through indications, evidence review, device description, procedural techniques to follow-up care and complications More than 40 high definition videos, hosted on companion website www.wiley.com/go/kipshidze/interventionaltherapies, complete with tips and tricks, provide a visual learning tool

ABC of Resuscitation is a practical, illustrated guide to the latest resuscitation advice for the non-specialist and provides the core knowledge on the treatment of cardiopulmonary arrest. This edition provides a guide to the European Resuscitation Council Guidelines for Resuscitation 2010 and the Resuscitation Council (UK) 2010 Resuscitation Guidelines. It Includes: the causes and prevention of cardiac arrest basic and advanced life support for adults, children and newborns resuscitation in a range of contexts (in-hospital and out-of-hospital, including drowning, pregnancy, sport and trauma) important aspects of implementation of guidelines including human factors and education ABC of Resuscitation, 6th Edition is ideal for all healthcare professionals including junior doctors, medical students, general practitioners, paramedics and nurses. It is also useful for pre-hospital care practitioners, emergency medicine trainees, resuscitation officers and all those who teach resuscitation. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.

Global movement of people leads to the global movement of disease International travel enables skin diseases to move around the world with increasing ease. Skin diseases transmitted through casual contact with people, animal vectors and a foreign environment are particularly prone to transport. Dermatologists need to recognize the signs and symptoms of disease not native to their environment to enable proper diagnosis and care. Imported Skin Diseases provides a clinical guide to the foreign diseases increasingly seen in ‘Western’ clinics. With a focus on accurate diagnosis and effective therapy, the book covers: Differences between pigmented and non-pigmented skin Viral, bacterial and fungal Infections Parasitic infestations Sexually transmitted diseases Aquatic diseases Written by an international team of experts, with practical tips throughout, Imported Skin Diseases prepares you for the unusual skin diseases you are increasingly likely to see in your clinic.

Lecture Notes: Psychiatry provides a concise and accessible introduction to the fundamentals of Psychiatry, presenting the principles of Psychiatric examination followed by systematic coverage of the major psychiatric disorders, as well as covering management and treatment options. This eleventh edition has been revised to include recent developments in history-taking, psychotropic drugs and case presentations, as well as covering the practical elements of patient guidance and care. Key features include: • Clearly presented tables, figures and end-of-chapter ‘Key point’ summaries to aid revision • An emphasis on core management skills needed by Junior Doctors in both psychiatric and general hospital settings • Quick reference guides to help structure patient assessments on-the-go • MCQs and case studies in line with medical school and professional level psychiatry exams For those embarking on study or refreshing their knowledge of psychiatry, Lecture Notes: Psychiatry provides a step-by-step guide to both its wider and patient-centred practice.

Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases. Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including: • Common inflammatory skin diseases • Skin cancer, moles and actinic keratoses • Infective skin disease, exanthems and infestations • Disorders of pigmentation In addition, many of the rarer skin disorders are also included so as to provide comprehensive coverage of the topic. World-leading experts in dermatology follow a clinical approach for each disease, and as well as providing their expert guidance on the description and diagnosis of dermatologic disorders, they also discuss common dilemmas that clinicians face when considering the best approach to patient management. ‘Key Points’ accompany each chapter to provide a quick review of the most important points. Clinically oriented and practically focused, Evidence-based Dermatology ensures that your treatments are entirely patient-focused and fully supported by the very latest medical evidence.

First published in 1958, Diseases of Swine, Tenth Edition is a fully revised and updated version of this classic reference. Now published in association with the American Association of Swine Veterinarians, the Tenth Edition adds new knowledge throughout in a reorganized format to provide more intuitive access to information. With chapters written by more than 150 of the foremost experts in the field, Diseases of Swine remains the premier source of comprehensive information on swine production, health, and management for swine health specialists of all disciplines and at any level of expertise, including veterinarians, researchers, and students. Featuring a new content organization designed for improved navigability, the Tenth Edition adds chapters on the cardiovascular system, diagnostic tests and test performance, food safety and zoonotic diseases, show and pet pigs, and the most current information on both long-recognized and emerging pathogens. Diseases of Swine, Tenth Edition is an indispensable resource for anyone interested in swine health.

Textbook of Pharmacoepidemiology, Second Edition, provides an introduction to pharmacoepidemiology and the data sources, methods and applications used in clinical research, the pharmaceutical industry and regulatory agencies. Drawing upon the fifth edition of the authoritative reference, Pharmacoepidemiology, this new edition covers the key learning requirements of the discipline. The textbook provides an introduction to pharmacoepidemiology, pharmacoepidemiological data sources, special issues in methodology, special applications and future developments in the field. Updated learning features such as case studies, key points and Suggested Further Reading are included throughout the text. Textbook of Pharmacoepidemiology is a practical educational resource for upper-level undergraduates, graduate students, post-doctoral fellows in schools of public health, pharmacy and medicine, and for everyone learning and working in pharmacoepidemiology.

Medical Decision Making provides clinicians with a powerful framework for helping patients make decisions that increase the likelihood that they will have the outcomes that are most consistent with their preferences. This new edition provides a thorough understanding of the key decision making infrastructure of clinical practice and explains the principles of medical decision making both for individual patients and the wider health care arena. It shows how to make the best clinical decisions based on the available evidence and how to use clinical guidelines and decision support systems in electronic medical records to shape practice guidelines and policies. Medical Decision Making is a valuable resource for all experienced and learning clinicians who wish to fully understand and apply decision modelling, enhance their practice and improve patient outcomes. “There is little doubt that in the future many clinical analyses will be based on the methods described in Medical Decision Making, and the book provides a basis for a critical appraisal of such policies.” – Jerome P. Kassirer M.D., Distinguished Professor, Tufts University School of Medicine, US and Visiting Professor, Stanford Medical School, US